New Work on Simultaneous T1-weighted and T2-weighted 3D MRI using RF phase-modulated gradient echo imaging

This study proposes a novel method for simultaneous T1w and T2w imaging using RF phase-modulated 3D gradient-echo imaging. T1-weighted and T2-weighted (T1w and T2w) imaging are essential sequences in routine clinical practice to detect and characterize a wide variety of pathologies. Many approaches have been proposed to obtain T1w and T2w contrast, although many challenges still remain, including long acquisition time and limitations that favor 2D imaging.


Proposed reconstruction scheme used in this study. To remove background phase, two acquisitions with opposite RF phase increments are acquired. These images are modulated with specific phase of Ψ1 and Ψ2 to improve T1w and T2w contrast. Finally, T1w and T2w images were calculated through addition and subtraction of modulated images.


Tamada D, Field AS, Reeder SB. Simultaneous T1 -weighted and T2 -weighted 3D MRI using RF phase-modulated gradient echo imaging. Magn Reson Med. 2021 Nov 9. doi: 10.1002/mrm.29077. Epub ahead of print. PMID: 34752639. DOI:10.1002/mrm.29077.