University of Wisconsin–Madison

Year: 2025

New work demonstrates explanted liver model for validating quantitative MRI method

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A new paper from Simchick et al. has demonstrated the feasibility of using perfused explanted human livers for validating a quantitative MRI-based technique which evaluates tissue microstructure and microvascular flow (i.e., intravoxel incoherent motion (IVIM) MRI). Explanted livers from deceased donors were connected to a perfusion system via the portal vein and hepatic artery, and MRI was performed under various highly controlled flow conditions. Using …

ISMRM 2025 Awards

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Two abstracts from the team were selected this year for cum laude awards, both led by Garrett. Congratulations! Fullerton GC, Tamada D, Muslu Y, Hernando D, Reeder SB. Saturation Recovery Chemical Shift-Encoded T1 Mapping in the Liver. Oral Scientific Session. International Society of Magnetic Resonance in Medicine (ISMRM) Annual Meeting. Honolulu, Hawaii, United States. May 14, …

Dr. Diego Hernando joins ranks of ISMRM Fellows of the Society

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Diego was named a Senior Fellow at this year’s ISMRM annual meeting for his contributions to quantitative MRI biomarkers of the abdomen and liver. This distinction is conferred on those who have made a significant and substantial contribution to research in a field within ISMRM’s purposes, who have contributed in a significant manner to the …

PDFF was the most accurate single classifier for diagnosing MASLD, MASH, and fibrotic MASH in patients undergoing weight loss surgery.

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Prior work has shown that MRI-derived proton density fat fraction (PDFF) can diagnose metabolic dysfunction-associated steatotic liver disease (MASLD) noninvasively, but there is a paucity of data on the performance of PDFF to classify more advanced forms of the MASLD spectrum. In collaboration with the Liver Imaging Group at UCSD, patients undergoing weight loss surgery …